WMicrotracker ONE is optimized for measurements of animals cultured in a liquid medium by using a 96- or 384-well plate format. Compatible with most small animal species [from 100um to 3mm size]. Useful for Drug screening, Mutant / RNAi screening, Oxidative Stress, Neurodegeneration, Developmental toxicology, Ecotoxicity experiments and more.
Based on an innovative system of 384 IR microbeams, the system detects the small interferences generated by the organisms present in the sample. In this way, a pattern of activity is recorded and processed using software specifically designed for real-time data acquisition. The digital analysis of signal changes (proportional to light intensity) allows us to detect the movement of the organism as it passes through the beam of light. An algorithmic software calculates the number of activity events per unit time.
1. FOR WHAT?
Experiments based on measurements of behaviour and viability. Mainly designed for liquid culture medium and multiwell plates of 96 and 384 wells. Flexible animal models: 0.1-10 mm. which have swimming movements.
2. FOR WHOM?
For any early stage or experienced laboratory. With affordable price for small laboratories. Focused on a varied field of experimentation. Intended for the academic and research sector, university teaching and for companies.
3. HOW DOES IT WORK?
The system detects the movement of organisms through the interference caused by them in an array of micro beams of infrared light. (Patented Technology # US12515723, EP208640881).
In C. Elegans
Triazole Fungicides Inhibit Zebrafish Hatching by Blocking the Secretory Function of Hatching Gland Cells. De la Paz JF, Beiza N, Paredes-Zúñiga S, Hoare MS, Allende ML.Int J Mol Sci. 2017
MD & PhD Thesis using WMicrotracker
Evaluation of WMicrotracker for assessing C. elegans stress responses. Hengyi Zhu. 2016. University of Oslo. Master thesis.
Natural Variation in Lifespan and Stress Responses in Caenorhabditis elegans. Jana J Stastna. Canterbury Christ Church University. 2016
Étude de la toxicité causée par le gène C9orf72 dans la Sclérose Latérale Amyotrophique. Par Martine Therrien. univeridad de Montreal 2016
Validación del sistema WMicrotracker en la evaluación de la capacidad antihelmítica de fármacos utilizando el organismo modelo Caenorhabditis elegans. Ladós Saldain, Enrique Néstor. Univ. de la República. Facultad de Veterinaria. Uruguay. Master Thesis. 2015